• Skincare cream tube with yellow cream swatch on a white background
  • Spicule Retinol PDRN Cream packaging with text on a gray background
  • Three tubes of Mary & May eye cream on a yellow background
  • Skincare product with text highlighting Spicule, Retinol, and PDRN, and a close-up of the product on a white background.
  • Advertisement for MPS Spicule with text and images of spicules on a white background
  • Skincare tube with a yellow label on a white background
  • 3-step delivery system for skincare with text and product images.
  • Product packaging with text about natural micro-spicules, nano-liposomal technology, retinol, and CICA PDRN on a dark background.
  • Woman's face with skincare product, showing visible clinical results on a yellow background
  • Yellow gel product with 'Natural Yellow Tint' label on a yellow background
  • Skincare product with 'Sensitive Skin Irritation Test Completed' and 'Dermatologically Tested' badges on a gray background.
  • Two skincare serum tubes with a box on a gray background
1 12

Mary & May

Mary & May Spicule Retinol PDRN Cream 15g

Mary & May Spicule Retinol PDRN Cream 15g

R 349.00 ZAR
R 349.00 ZAR
Sale Sold out
Taxes included. Shipping calculated at checkout.

The Mary & May Spicule Retinol PDRN Cream is a nighttime treatment cream formulated with retinol, PDRN and niacinamide. It improves the appearance of fine lines, uneven texture and dullness while supporting smoother and firmer-looking skin.

The lightweight yet nourishing texture works as the final step in an evening skincare routine. Ideal for skin that appears tired, rough or showing early signs of ageing.

Apply at night as the final step of your skincare routine. Use sunscreen during the day.

View full details
✓ 100% Authentic Products
🚚 Fast Nationwide Delivery
✨ Curated For Your Skin
🔒 Secure Checkout

FAQs about Mary & May Spicule Retinol PDRN Cream 15g

Skincare cream tube with yellow cream swatch on a white background

What are spicules?

Spicules are micro-particles that help boost product absorption into the skin.

Will it irritate my skin?

A mild tingle is normal due to retinol and spicules. Start slowly.

Can I use it nightly?

Build up to nightly use after starting 2–3 times per week.

Is the 15g size enough?

Yes — a little goes a long way with this concentrated formula.

What are the key ingredients?

Retinol, PDRN and Niacinamide.